“Much of what medical researchers conclude in their studies is misleading, exaggerated, or flat-out wrong. So why are doctors — to a striking extent — still drawing upon misinformation in their everyday practice? Dr. John Ioannidis has spent his career challenging his peers by exposing their bad science.” “Science is a noble endeavor, but it’s also a low-yield endeavor,” Dr. Ioannidis says. “I’m not sure that more than a very small percentage of medical research is ever likely to lead to major improvements in clinical outcomes and quality of life. We should be very comfortable with that fact.”