Daphne Koller is the founder and CEO of insitro, where machine learning is applied to drug discovery and development. She also co-founded the digital learning platforms Coursera and Engageli. Koller spent 18 years as a professor of computer science at Stanford University, earning the Stanford Medal for Excellence in Fostering Undergraduate Research, and now serves as an adjunct faculty member. She was previously chief computing officer at Calico.

She was named a MacArthur Fellow in 2004. She's also been inducted into the National Academy of Engineering, the American Academy of Arts and Sciences, the International Society of Computational Biology, and the National Academy of Sciences. She has authored more than 300 peer-reviewed publications in journals including Science and Cell and was named one of TIME’s 100 most influential people in AI in 2024.