Aging Mechanisms

Aging Mechanisms

A man with short hair and a beard, wearing a light blue button-up shirt, sits indoors in front of a wooden wall.
21mins
"By keeping people biologically younger, we can enjoy a longer health span, a longer period of healthy life where we're active, where we're happy, where we can engage in our hobbies, and play with our grandkids and great grandkids."
A woman sits on a chair in front of a white backdrop in a brick-walled room, with potted plants on tables on either side.
54mins
Members
"This will help people take meaningful steps to slow the rate of aging and increase what we call their health span or their kind of time of life expectancy free from disease."
Green decorative geometric shape with the text "Rewriting the Rules of Life" written in black serif font across the center on a light green background.
15mins
“Until very recently, I thought I would die with the same genome that I was born with.”
A close up of a hand.
13mins
“Over the last 10 or 15 years, scientists have really started to understand the fundamental underlying biology of the aging process. And they broke this down into 12 hallmarks of aging.”
A man sits on a chair in a photo studio, flanked by black-and-white illustrations of an early human ancestor on the left and a modern man running on the right.
1hr 13mins
“Nothing about human behavior makes sense except in the light of culture and in anthropology, and we need to understand the cultural component to our behaviors as well.”
A worker in protective gear operates machinery in an industrial facility, with a partial overlay of solar panels and geometric patterns above—hinting at the innovative spirit found in stellar societies.
The cofounders of think tank RethinkX are convinced that humanity is undergoing civilizational phase change.
Orange spherical cell with elongated extensions against a black background.
Some go gently into the night. Others die less prettily in freak accidents or deadly invasions, or after a showy display.
Person flexing arm muscles with a photo-negative effect applied, overlaid with semi-transparent geometric shapes. Person is facing away, showing arm and shoulder. Background is indistinct.
While GLP-1 agonists help people lose weight, different drugs could help them retain muscle at the same time.
Two elderly women walking alongside and interacting with a statue of a man holding a briefcase.
A growing body of research suggests that optimism plays a significant role in promoting both physical and mental well-being.
A bottle of Coca Cola on a red background.
If you eat a diet full of refined grains, high-sugar drinks, and sweets, there's a good chance you have too much insulin.
A woman holding a baby's hand, symbolizing the bond between families.
Smaller family networks, more great-grandparents, and fewer cousins.
A man is walking towards a crate with the number 60 on it.
6mins
People are living longer than ever, challenging our assumptions around milestones like retirement. Economist Lynda Gratton explains a “multi-stage life,” and how retiring later isn’t necessarily something to fear.
The baskets are filled with different kinds of vegetables.
Antioxidant vitamins don’t stress us like plants do—and don’t have their beneficial effect.
A white rat with long hair standing on a black background.
A new study provides the first proof-of-principle that genetic material transferred from one species to another can increase both longevity and healthspan in the recipient animal.
A woman wearing a sleep apnea mask with a bottle of water.
If not treated, the disorder drastically increases one's risk of death.
An elderly woman sitting on a chair and talking on the phone.
Interventions can make the most difference when Alzheimer’s is detected early.
two hands reaching for each other on a black background.
3mins
Age expert Dr. Morgan Levine explains why living to 100 is the wrong goal.
a birthday cake with the number 100 on it.
4mins
Former Yale professor Dr. Morgan Levine shares 3 ways to change your diet to extend your life.
a drawing of a man with his gut microbiome highlighted.
A secret to a long, healthy life may lie in the diversity of gut viruses, which can supercharge bacterial metabolism and resist disease.
an old man flexing
It’s safe to use your face cream, as long as you aren’t eating it.
two hands reaching for each other with the words your true age.
9mins
Your chronological age and your biological age aren’t the same thing. This ex-Yale professor explains how to tell the difference.
a multicolored image of a cell phone.
Rapamycin is potentially the most powerful anti-aging drug ever discovered. However, due to its unlucky history, few know of it.
Our brainwaves naturally synchronize with external stimuli like flickering lights. Here's how the phenomenon might boost learning.
a bat hanging upside down in a tree.
By studying the oldest animals, researchers hope to pinpoint factors affecting human longevity.
a man sitting on the bow of a sailboat.
Biological age is a better health indicator than the number of years you’ve lived, but it’s tricky to measure.
a diagram of a human skeleton and a dumbbell.
Having a "buff" skeleton prevents infirmity in old age.
The body uses its own electricity to repair wounds. Faster healing may be possible with additional electrical stimulation.
Epigenetic entropy shows that you can’t fully understand cancer without mathematics.
No family is immune to money conflicts, no matter how much they love each other. Here’s what to look out for.