“Psychedelics crosscut so many interesting domains. They've been used for time immemorial by indigenous cultures. In our own Western cultural history, they really exploded on the scene in the 1960s, and were associated with radical changes to society.”

What happens when the boundaries of “you” disappear? James Fadiman, PhD, Jamie Wheal, and Matthew Johnson, PhD explore how supported experiences with psychoactive drugs can dissolve identity and reveal a deeper reality.

Psychiatrist Dr. Bessel van der Kolk discusses key methods for rewiring the brain, kickstarting the healing process, and opening your mind to new perspectives.

A look inside Mindstate Design Labs' effort to design drugs that reliably produce specific states of mind.

A powerful psychedelic long used in African rituals shows surprising promise for treating traumatic brain injury and PTSD.

MAPS founder Rick Doblin speaks to Big Think about the FDA’s rejection of MDMA therapy and the future of psychedelic treatments.

"Upon emergence, these patients are sincerely unsure what was reality and what was a ‘dream.'"

Fixing chronic pain in the body may sometimes require a treatment focused on the brain.

A recent study suggests that exposure to visual stimuli can diminish the effects of psychedelic drugs.

Here's the thorny reality behind psychedelics' ability to unearth buried memories.

The heart's rhythms may play a larger role in shaping psychedelic experiences than previously thought.

What a long strange trip it's been.

What hallucinogens will make you see.

The benefits of the psychedelic seem to last long after the trip wears off.

In a psychedelic state, the relationship between your “narrative” and “minimal” selves seems to transform in unique ways.

Why does the DMT experience feel so familiar to some people — even those who are trying the psychedelic for the first time?

There were many similarities, but also some profound differences.

Johns Hopkins professor Dr. Matthew Johnson answers 24 huge questions about psychedelics.

Neuroscientists and artists alike are making the case that we could transform the world through psychedelics.

Ketamine-assisted psychotherapy utilizes a non-ordinary state of consciousness to heal.

Tasting sounds and hearing colors.

A new study provides the most detailed look at brains on psychedelics to date.

Psychedelics mess with our prior beliefs, and could help us see what forms these beliefs in the first place.

End of life patients face mental health challenges uniquely existential and spiritual in nature — but psychedelics are emerging as a possible solution to relieve the suffering.

Depression might be similar to dreaming.

New research shows psychedelics activate receptors inside brain cells that other compounds, like serotonin, cannot.

The initial study lays the groundwork for another larger, longer phase 2 trial.

Belief in God and the afterlife increased, while belief in superstition decreased.

Our society is in a mental health crisis. Are psychedelics the way out?

Can psychedelics solve the ‘hard problem’ of consciousness? A Johns Hopkins professor explains.