The Santa Fe Institute is a cradle of modern research. Our host Kmele meets some of the brilliant minds who work there.

He co-created one of TV’s funniest shows. He still felt like a failure in his 30s. This is comedian Neal Brennan’s story about conquering toxic self-talk.

Combining years of neurological research and mindfulness techniques, Dr. Heather Berlin helps us better understand how the body’s most complex organ can easily be misled into negative thinking – and how we can stop that from happening.

The NFL icon talks overcoming a difficult childhood and what’s needed to succeed in a world where the cards are stacked against you.

Our host Kmele went inside Fermilab, America’s premiere particle accelerator facility, to find out how the smallest particles in the universe can teach us about its biggest mysteries.

There are three kinds of failure. Only one can help you have a better shot of succeeding in the future. A Harvard business professor explains.

“Only a narcissist would want to become president.” This is the psychology of an authoritarian unpacked.