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Immune Response
By treating the human body as an information system, scientists are using AI to simulate cells, visualize hidden biology, and detect disease at its earliest — and most preventable — stages.
Biohub
54mins
“How can all the diversity and, sort of, seeming order that's out there in the world emerge from a process dependent upon chance?”
In "The Microbiome Master Key," Brett and Jessica Finlay argue that we need to stop waging war on all germs and start working with the microbes that make us who we are.
For centuries, vaccines have been the top life-saving, expert medical intervention known to humans. How can individuals make the right call?
“If we could target those circuits very precisely, then there’s great potential to block the inflammation response for many diseases."
Growing evidence suggests a link between the debilitating neurological illness and the microbes that live in our intestines. The vagus nerve may be a pathway.
People with higher immune resilience live longer, resist diseases, and are more likely to survive diseases when they do develop.
It temporarily puts the immune system on high alert to prevent MRSA, pneumonia, and other infections in the hospital.
Boys are four times as likely as girls to develop autism. Girls are nearly twice as likely to experience depression. The immune system may be a player in these and other brain-health disparities.
Some scientists think we should allow our bodies to more harmlessly live with pathogens until they’re cleared from our systems.
Gum disease begins in the mouth but spreads to the joints. Rheumatoid arthritis is just one of several diseases linked to poor oral health.
Once activated, the CRISPR-Cas12a2 system goes on a rampage, chopping up DNA and RNA indiscriminately, causing cell death.
People with shingles have an approximately 80% higher risk of stroke than those without the disease.
"Jumping genes" exist in various forms, including as remnants of ancient retroviruses, and make up about 45% of the human genome.
This small phase 1 study suggests that CRISPR-engineered T cells are safe and potentially effective, but there is a long way to go.
When we feel sick, it's not just the pathogen to blame. Our brain cranks up the temperature, and the neurons responsible finally have been found.
A successful trial that tested a vaccine against bladder cancer in dogs could help develop a similar one for humans.
Drugs that stifle acute inflammation may prevent the body from healing properly.