Translational Medicine

Translational Medicine

Green decorative geometric shape with the text "Rewriting the Rules of Life" written in black serif font across the center on a light green background.
15mins
“Until very recently, I thought I would die with the same genome that I was born with.”
Illustration of a person walking inside a brain silhouette, overlaid on a close-up of closed eyes.
Locked inside their minds, thousands await a cure. Neuroscientist Daniel Toker is racing to find it.
Overlay of hands with abstract purple and black lines in the background.
“The field is endless, but my life is limited, as are all of ours. But you do what you can with your time,” says CSO Mart Saarma.
Illustration of a hand cutting red tape with scissors over a government building labeled "National of Health.
There is one obstacle that reliably blocks innovative ideas: how we fund science.
A 3D structural representation of a protein with intertwined helices and strands, depicted in shades of pink and purple, set against a black background.
"By 2040, we hope to see a number of new drugs that have been designed with AI reaching patients."
Abstract orange and pink collage with intricate line drawings of human figures and anatomical details, connected by white lines.
“If we could target those circuits very precisely, then there’s great potential to block the inflammation response for many diseases."
Transparent perfume bottle surrounded by floating pink spheres with intricate patterns on a dark background.
Vaccines targeting some of our deadliest cancers are showing promise in early trials.
A lepodisiran image of a human heart on a black background.
There is currently no easy way to treat high Lp(a). A single shot could change that.
EBT-101 is not the only candidate for an HIV cure. Stem cell transplants, medications, and other CRISPR therapies are being researched.
A woman wearing a lab coat researching non-hormonal birth control options.
Since the 1980s, engineered monoclonal antibodies have been knocking out invading germs. Sperm may be next.
A doctor is examining a boy's eye.
The topical gene therapy could one day help millions regain their vision.
Gum disease begins in the mouth but spreads to the joints. Rheumatoid arthritis is just one of several diseases linked to poor oral health.
rational vaccinology
"Rational vaccinology" could lead to effective cancer vaccines.
Researchers have been developing a promising model that can more closely mimic the human body – organ-on-a-chip.
More work is needed before declaring the technique a fountain of youth.
What if you could just grow your own blood?
covid drug
A new drug inhibits a human enzyme that coronaviruses hijack in order to replicate.
fear
The research could aid the development of more effective treatments for conditions such as post-traumatic stress disorder (PTSD). 
crispr cancer therapy
This small phase 1 study suggests that CRISPR-engineered T cells are safe and potentially effective, but there is a long way to go.
The "love hormone" might be an unexplored treatment for Alzheimer's disease and other forms of dementia.
herpes cancer
Biotechnology can convert enemy viruses into anti-cancer mercenaries.
The new agency wants to push the boundaries of science and technology.
hiv vaccine
HIV mutates rapidly, which has made the development of a vaccine an enormous challenge for decades. Finally, we might have one.
universal coronavirus vaccine
The antibodies elicited by the "S2 vaccine" not only neutralize COVID's multiple strains but also coronaviruses that cause the common cold.
crispr cholesterol
It could permanently lower cholesterol — and permanently reduce your risk of having a heart attack.
dog cancer vaccine
A successful trial that tested a vaccine against bladder cancer in dogs could help develop a similar one for humans.
neuropathic pain
Scientists found a way to revert pain in mice using gene therapy. Perhaps the same technique could be applied to humans.
chronic pain
Drugs that stifle acute inflammation may prevent the body from healing properly.