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Translational Medicine
15mins
“Until very recently, I thought I would die with the same genome that I was born with.”
Locked inside their minds, thousands await a cure. Neuroscientist Daniel Toker is racing to find it.
“The field is endless, but my life is limited, as are all of ours. But you do what you can with your time,” says CSO Mart Saarma.
“If we could target those circuits very precisely, then there’s great potential to block the inflammation response for many diseases."
EBT-101 is not the only candidate for an HIV cure. Stem cell transplants, medications, and other CRISPR therapies are being researched.
Since the 1980s, engineered monoclonal antibodies have been knocking out invading germs. Sperm may be next.
Gum disease begins in the mouth but spreads to the joints. Rheumatoid arthritis is just one of several diseases linked to poor oral health.
Researchers have been developing a promising model that can more closely mimic the human body – organ-on-a-chip.
The research could aid the development of more effective treatments for conditions such as post-traumatic stress disorder (PTSD).
This small phase 1 study suggests that CRISPR-engineered T cells are safe and potentially effective, but there is a long way to go.
The "love hormone" might be an unexplored treatment for Alzheimer's disease and other forms of dementia.
HIV mutates rapidly, which has made the development of a vaccine an enormous challenge for decades. Finally, we might have one.
The antibodies elicited by the "S2 vaccine" not only neutralize COVID's multiple strains but also coronaviruses that cause the common cold.
A successful trial that tested a vaccine against bladder cancer in dogs could help develop a similar one for humans.
Scientists found a way to revert pain in mice using gene therapy. Perhaps the same technique could be applied to humans.
Drugs that stifle acute inflammation may prevent the body from healing properly.